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doi: 10.1016/0168-8278(90)90072-Y 12 SollowayMJMadjidiAGuCEastham-AndersonJClarkeHJKljavinNet al

[10] [12] Concomitant use with aluminum-containing antacids may increase aluminum absorption, especially in patients with renal impairment

Maintaining Long-Term Appetite Control After 4 to 8 weeks, appetite suppression typically plateaus at a consistent level where hunger remains dramatically reduced compared to baseline

R.et al (1991)