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A daily oral (pill) version of semaglutide, Rybelsus, was approved for type 2 diabetes treatment in 2019

The pilot clinical data is consistent with the mechanism

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Specifically, this can include the big four: Nausea Diarrhea Vomiting Constipation Also relatively common are abdominal pain and dyspepsia (discomfort or pain in the upper abdomen after eating or drinking)

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In clinical trials, patients who used Ozempic for weight loss experienced significant reductions in body weight, typically ranging from 10-15% over a year