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In severe cases of BPH, surgical intervention may be necessary, such as transurethral resection, in which excess prostate tissue is removed, enucleation of the prostate and open prostatectomy

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The most common issues reported by users of GLP-1 medications include nausea, bloating, and changes in bowel habits

Phase II Clinical Data Jastreboff 2023 (NEJM) reported 24.2% bodyweight reduction at 48 weeks - the largest effect size published for any metabolic peptide in clinical trials

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