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It is important in the glucose metabolism, protects the mitochondria from oxidative stress and glycation, and altered glomerular function, as well as modifying the inflammatory response pathway and activation of the polyol pathway (a part of intracellular signalling and metabolism) and currently prescribed Somac therefore advisable to check status

In a different multicenter, randomized, double-blind, placebo-controlled trial, Ziegler and co-workers examined the effects of ALA on neuropathic deficits and positive sensory symptoms in patients with diabetes with distal symmetric polyneuropathy [76]

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This aligns with research: modest effect, mild side-effects, require lifestyle support and good monitoring