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Because that is when gastrointestinal effects peak, according to the article

If you have diabetes and are also taking insulin or sulfonylureas, monitor your blood glucose levels regularly, as your requirements for these medications may decrease

These benefits appeared to stem from the modulation of enteric neuronal function and tight junction expression

This is not the time to experiment

282,283 Similarly, tirzepatide decreased left ventricular mass and paracardiac adipose tissue in patients with obesity-associated heart failure, corresponding with a reduced risk of heart failure events

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