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While researchers have yet to fully explain how high folate intake is a natural remedy for high blood pressure, we do know that folic acid reduces homocysteine levels, and high homocysteine levels are toxic to blood vessels in the brain and heart

Studies have suggested that increased susceptibility to KBD in selenium-deficient populations might result from a reduced antioxidant protection associated with polymorphisms in GPX genes (60, 61), but polymorphisms in other genes have also been implicated (62)

doi: 10.1002/j.1460-2075.1991.tb07761.x 59 SemenzaG

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