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Another study of 60 healthy adult women found that topical application of a cream containing L-glutathione and vitamin C led to significant improvements in skin elasticity, roughness, and hydration

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Xue M, Shi M, Xie J, Zhang J, Jiang L, Deng X, et al

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This designation allows the use of these compounds strictly for in-vitro laboratory testing and experimentation

Williams, A novel role for vitamin B12: Cobalamins are intracellular antioxidants in vitro, Free Radical Biology and Medicine, Volume 47, Issue 2, 15 July 2009, Pages 184-188, ISSN 0891-5849, J