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9598 Mechanistically, in the absence of impaired kidney function, more than 95% of TMAO in the human body is excreted through renal tubules or glomerular filtration, 99,100 suggesting a potential mechanism for elevated circulating TMAO levels when renal function is impaired

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Currently, the matrix-formatted output includes: If you additionally use the --add-per-population-copy-number flag (only available with an external-genomes file), you will get two more matrix files describing pathwise and stepwise per-population copy number (PPCN), plus a -POPULATION-ESTIMATES.txt file reporting the population count estimates used for normalization