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Introduction Iron is a vital trace element for all living cells

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These cells detect the presence of nutrients in the intestinal lumen via chemosensory G protein-coupled receptors (GPCRs) and taste receptors , and in response, release hormones that influence digestion , appetite , and glucose metabolism

The capacity to oxidize medium-chain fatty acids via the mitochondrial -oxidation pathway is partially preserved in patients with CPT2 deficiency due to the lack of a strict requirement for medium-chain fatty acids to be attached to carnitine for entry into the mitochondrial matrix

Include fiber-rich vegetables and legumes, which feed gut bacteria that produce GLP-1-stimulating compounds

doi: 10.1056/NEJMoa2403664