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The compound's sleep-promoting and related general physiological effects after intraventricular (brain), intravenous, and intraperitoneal application in different mammalian species have since been confirmed

2008 Nov 29;372(9653):1906-1913

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Ge, Y., Rybakova, I

doi: 10.1016/j.cell.2020.02.015

Absolutely, but in an indirect way