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Compared with controls, treatment of senescent chondrocytes with B2M-CuS NPs resulted in reduced expression of anti-apoptotic Bcl-2 and increased expression of pro-apoptotic Bax (Fig

vemurafenib 5 days/week, 10 mg/kg) and BRAFi+MEKi group (vemurafenib 5 days/week, 10 mg/kg

Dosing Schedules from Published Research Phase 2 Trial Dose Groups The Phase 2 clinical trial published in NEJM employed the following dose groups, all administered via subcutaneous injection once weekly: Scroll sideways to view the full table on mobile

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(TIFF 101 kb) Supplementary Figure 4 (download TIF Confirmed transcript variants of GSTT1, GSTT2 and GSTZ1

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