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Therefore, NRF2 plays an important role in maintaining the cell redox balance and preventing ferroptosis

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Chen, L., Jia, L., Zhang, Q., Zhou, X., Liu, Z., Li, B., et al., Anaerobe , 2017, vol

In addition, the TNF-/NF-B pathway was also implicated in up-regulating voltage-gated sodium channels, such as Nav1.7, in dorsal root ganglion neurons, contributing to the chronic pain experienced in DN (Huang et al., 2014)

Common Symptoms and Complications Symptoms of thalassemia range from mild to severe