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Hydration - Dr

The atypical energy-related symptom (AES) profile is based on the five items of hypersomnia, increased appetite, increased weight, low energy and leaden paralysis (range 015)

doi:10.1016/S0167-4781(00)00067-1 3

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AMPK activation during energy deficiency can both inhibit ferroptosis, through phosphorylation of ACACA/ACC (acetyl-CoA carboxylase alpha) in MEFs (mouse embryonic fibroblasts) and human renal adenocarcinoma cells [68], and promote ferroptosis, by targeting BECN1 (beclin1)-mediated system xc - inhibition in human colorectal cancer cells [25] or regulating pyrimidinosome assembly in human cervical cancer cells [69]

PMID 17895430