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Participants receiving semaglutide 2.4 mg weekly achieved an average body weight reduction of approximately 14.9%, compared to 2.4% in the placebo group

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Nora Volkow, director of the National Institute on Drug Abuse at the National Institutes of Health, who has done similar work analyzing medical records to assess GLP-1 drugs

The creatine group increased lean body mass by an average of 1.32 kg compared to placebo

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As suggested by Wang et al., metformin may play an important role in the quality-control regulation of mitochondria and shift the cellular dynamics to a healthy population via mitophagy and eliminate damaged mitochondria (138) [see also (148)]