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A systematic review and meta-analysis used to inform international PCOS guidelines discusses potential benefits and limitations (Fitz et al., 2024) in PubMeds record for the review

Vitamin B12 (cobalamin) is essential for red blood cell formation, neurological function, and cellular metabolism, but supplementation does not directly cause fat reduction or appetite suppression

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Order it with serum iron, transferrin or TIBC, transferrin saturation, complete blood count (CBC), and a basic inflammation marker like CRP