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[8] Similarly, patients with gout or hyperuricemia should avoid high niacin intake, as niacin (even in nicotinamide form) can raise uric acid levels and potentially trigger gout flares

Because it leaves a clean, bare-skin finish, it will not pill under your makeup during the day or interfere with your thicker moisturizers and sleeping masks at nightHealthy skin requires consistency and care

However, it has not been proven to reduce appetite or promote weight loss

doi:10.1038/s41467-025-58680-y

Both studies administered B12 i.m., one used methyl-B12 at a dose of 500 g three times per week for 2 weeks, 63 the other used cyano-B12, 1000 g daily for 2 weeks