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10.3389/fpsyt.2022.930714 105 LonnE.BoschJ.YusufS.SheridanP.PogueJ.ArnoldJ

The duration of treatment is determined by the doctor and typically lasts 1-1.5 months

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Updated March 12, 2026

Moreover, at least 3 other cytoplasmic enzymes including isocitrate dehydrogenase 1 (IDH1), malic enzyme 1 (ME1) and 10-formyltetrahydrofolate dehydrogenase (ALDH1L1) contribute to NADPH synthesis in cytosol