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Similar content being viewed by others This article describes research in our and other laboratories on mitochondrial metabolism of acetyl-L-carnitine (LAC) that has led to the discovery of novel epigenetic mechanisms for the rapid regulation of brain plasticity in multiple rodent models and then has prompted us to uncover a role for this proposed mitochondrial signaling pathway of epigenetic function as a therapeutic target for clinical phenotypes of depression linked to childhood trauma, and implications for Alzheimers disease (Fig

Moreover, the adhesion of probiotic microorganisms to epithelial cells may trigger a signaling cascade, leading to immunological modulation (Markowiak and Sli, 2017)

They also noted that cells cultured with IGF-1 exhibited better morphology due to the increased number of gap junctions between theca-granulosa cells and granulosa cell-oocyte (61)

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Shaw, M

doi: 10.1152/ajpregu.00775.2005