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Secondary endpoints included the rate of patients with a weight loss of 10%, monthly headache days (MHD), the rate of patients with a 30% and 50% reduction in MHD, visual outcome parameters, and adverse events (AEs)

Within minutes after a meal, GLP-1 is released from the L cells in the ileum and colon and regulates insulin secretion in a glucose-dependent manner

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Given superior efficacy, retatrutide will likely command premium pricing, but calling it expensive Ozempic misunderstands both the chemistry and the economics

Additionally, our analysis could not discern the specific clinical indications for GLP-1RAs initiation during AKD due to the nature of database research, limiting our ability to fully contextualize prescribing decisions