This process decreases IS autoreactive potential by increasing Treg and decreasing Th17 ratio, which is a process opposite to vitiligo onset (Lotti et al., 2015
It upregulates the expression of early growth response protein 1 (EGR-1), a transcription factor that controls over 30 downstream genes involved in cytokine production, growth factor signaling, and extracellular matrix remodeling
Pull-down assay Pull-down assays were performed using Ni-NTA agarose beads (Qiagen) according to the manufacturers protocol
Near Infrared: Often dubbed the vanity wavelength, near-infrared is a discreet performer that goes deep without causing discomfort
The application of transcriptomics, animal models, and spatial analysis techniques has introduced novel strategies for elucidating their mechanisms of action
Immunology of the maternal-fetal interface