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These findings may contribute to a better understanding of the metabolic regulatory mechanisms of GLP-1 and dual GIP/GLP-1 receptor agonists while providing a theoretical basis for future BAT-targeted therapies

In patients who did not receive SGLT-2 inhibitors at baseline or during the study, 20.7% experienced the primary outcome with semaglutide and 27.2% experienced the primary outcome with placebo (HR 0.70, 95% CI 0.590.82) [24]

These benefits make it a potentially valuable supplement for maintaining energy levels while on semaglutide

Potential Side Effects Both medications can cause similar side effects, primarily gastrointestinal issues such as nausea, vomiting, diarrhea, and constipation

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