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Of note, this approach to ICP monitoring was chosen by the patient advisory group due to the negative impact reported by repeated lumbar punctures [23, 24], and the use within the trial was carefully discussed with the individual participants during the consent process

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Mice were sleep deprived in their home cage by light cage tapping and gentle stroking of the back using a small paintbrush

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[DOI] [PubMed] [Google Scholar] 29.Pinkney J, Fox T, Ranganath L