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GLP-1 injectable medications like Ozempic cost between $900 and $1,500 monthly without insurancea barrier for many patients seeking weight management and metabolic support
However, under conditions of iron overload, excess Fe 2+ in the LIP undergoes Fenton chemistry with H 2 O 2 , producing excessive ROS, promoting lipid peroxidation, and ultimately triggering ferroptosis (Zhao et al., 2025a)
Novo Nordisk launched the product in the United States in January 2026, marking the first time an oral GLP-1 treatment had been cleared specifically for weight management