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Journal of the Medical Library Association 2006;94(1):417

When tirzepatide earned FDA approval for obesity under the brand name Zepbound, it marked the first dual-action GLP-1/GIP therapy officially recognized for chronic weight management

Those who received the semaglutide lost close to 15 percent of their body weight, on average, compared to 2.4 percent among those receiving the placebo

SMJ contributed to conclusion and reviewed/edited manuscript

The Aib (2aminoisobutyric acid) residue at the Nterminus improves resistance to enzymatic degradation, while modified amino acids such as D2naphthylalanine and Dphenylalanine enhance laboratory stability