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Inability to keep any fluids down for more than 12 hours despite trying all management strategies

Patients should initially consult their GP, who can refer to local NHS eating disorder services, community mental health teams, or specialist weight management services as appropriate

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Thus the benefits of GLP-1 RA (and dual/tri agonists) on reductions in liver fat, favorable effects on renal function and favorable outcomes in HF trials have all been demonstrated in randomized clinical trials presented at these meetings

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[50,51] Potential biologics have been generated to target pro-inflammatory cytokines, such as IL-1, interferon (IFN)-, IFN-, IL-6, TNF-, IL-17, and IL-21, and several clinical trials that aim at inhibiting the activities of these mediators have been initiated