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Deviate from those conditions, and the effective shelf life shrinks

It is used prior to pregnancy and typically discontinued at an appropriate time during fertility planning

Other common symptoms include: Post-exertional malaise: Feeling worse after physical activity, often the next day Unrefreshing sleep: Waking up feeling unrefreshed, despite getting enough sleep Cognitive difficulties: Trouble concentrating and multi-tasking Orthostatic intolerance: Feeling lightheaded or experiencing a rapid heartbeat when standing up CFS/ME often involves cycles of flare-ups and remissions, with good days and bad days

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"Outcomes of mild therapeutic hypothermia after in-hospital cardiac arrest." Neurocritical care , 16(3), (2012) 406-12

EL is able to form oligomers that can assemble to linear or annular protofilaments [68]