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As the popularity of GLP-1 receptor agonists like Ozempic, Wegovy, and Mounjaro continues to surge, so do concerns about their safety

This machine works by removing your blood, separating out the plasma, and returning the blood back to your body

We employ variants of the peptides GLP-1 and exendin-4 to explore the interplay between helical propensity near the agonist N-terminus and the ability to bind to and activate the receptor

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The olfactory mucosa provides a pathway that partially bypasses the blood-brain barrier, delivering peptides to the central nervous system more efficiently than peripheral routes