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Most patients were female (61%) with an average baseline A1C of 8.5%, mean age of 69 years, and average weight of 99.2 kg
Approximately 75% of patients continue treatment after 12 months, indicating its effectiveness and acceptance in clinical practice for managing blood sugar levels and encouraging substantial weight loss
At 24 weeks, the mean weight reduction was 17.5% (41.2 lb)
The results were unlike anything shed tried before
158 Mendez-LopezI.Sancho-BielsaF
Pregnant subjects should also avoid semaglutide, based on animal studies that reveal GLP-1-RAs could reduce embryo size and cause developmental abnormalities [35]
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