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Weight change 1 year after the start of treatment was measured

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Estradiol-induced BAT thermogenesis and its consequent body weight loss can be prevented by activation of AMPK in the VMH (108)

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Exons 11 and 12 encode the antenna-like domain, which is located at the pivot helix of the GDH structure and adjacent to the GTP allosteric binding domain encoded by exons 6 and 7