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Delibegovic M, Zimmer D, Kauffman C et al (2009) Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress

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Magnitude of Weight Loss GLP-1 medications produce substantially more weight loss than older diabetes treatments: Semaglutide (diabetes doses): Average weight loss of 10-12% of body weight at the 1mg and 2mg doses used for diabetes