Variables included in the multivariate analysis were selected based on their statistical significance in univariate analyses
These findings suggest that older adults with Type 2 diabetes might benefit more from Jardiance in reducing heart failure hospitalization and major cardiovascular events, particularly those with a history of cardiovascular disease
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At the metabolomics level, the fatty acid biomarkers identified include capric acid, caproic acid, propionic acid, and heptanoic acid and showed a significant reduction in at least one of the severity groups listed above, compared to the healthy controls and the concentration of the uremic toxins IS and p-CS were significantly high at the advanced stage
doi: 10.1161/01.CIR.92.4.767