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Although data collection occurred at a single time point, patient recruitment and sample collection were prospectively conducted based on a pre-specified study protocol

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One small crossover trial found that morning semaglutide injections before 8am produced roughly 15% lower post-prandial glucose compared to evening doses after 8pm

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The most common ones include: Nausea Vomiting Diarrhea or constipation Stomach pain Fatigue Most side effects are mild and improve over time