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DOI:10.1016/j.freeradbiomed.2017.04.363 40
doi: 10.1016/0378-8741(88)90127-4 20 ChittendenRHJoslinEPMearaFS
Systemic effects include fluid retention, arthralgias, and peripheral edema consistent with GH excess
Animal toxicology studies across mice, rats, rabbits, and dogs have not reported major toxicity signals, and some published preclinical papers note that a lethal dose threshold was not reached in animal testing [17]
Keywords Trospium Trade Name: Sanctura Drug Class: quaternary muscarinic antagonist Mechanism of Action: Quaternary, nonselective muscarinic antagonist (inhibits M1-M5 receptors with similar potency)
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