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Proc Natl Acad Sci USA 79(2):345349

We will integrate evidence ranging from fundamental pharmacology and molecular mechanisms to divergent findings from epidemiological studies and large-scale clinical trials

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One study raised the question of a very small increased risk of AMD, while another found signs of protection

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In the sensitivity analysis, the rates of major birth defects, when all major anomalies irrespective of aetiology were included, were 3.1% in the GLP1-RA exposed group and 4.2% in the reference group with diabetes