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In the liver, GCGR signaling stimulates hepatic glucose production through glycogenolysis and gluconeogenesis, promotes lipolysis, and inhibits fat accumulation

[DOI] [PubMed] [Google Scholar] 86.Colhoun HM, et al

doi: 10.1016/j.bbamcr.2020.118883

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The initiation of ferroptosis requires a critical damage threshold, which is determined by the dynamic balance of multiple factors, such as the intracellular free iron concentration, lipid peroxidation levels, GSH reserves, and GPX4 activity

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