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The authors also validated that GSH content and GPX4 activity were significantly decreased when H22 cells were co-incubated with Mn-MOF (Figures 5H, I)

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Front Cell Infect Microbiol

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Its proposed mechanism inhibition of tyrosinase and a resulting shift from eumelanin to phaeomelanin synthesis is used to support gradual, systemic skin brightening and hyperpigmentation reduction, though individual results vary