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doi: 10.3390/cells13030248 196 ZengLYangKYuGHaoWZhuXGeAet al

However, nearly all data come from lab and animal studies rather than controlled human trials, so claims about systemic hormone changes warrant caution

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A broader 2020 review by Sikiric and colleagues in Gut and Liver frames the compound's proposed GI activity within Robert's cytoprotection and organoprotection model the longstanding physiological framework describing how the gastric mucosa protects itself against injury

10.1111/bph.12663 [DOI] [PMC free article] [PubMed] [Google Scholar] Fukuda K., Kato S., Mori K., Nishi M., Takeshima H., Iwabe N., et al

Several clinical trials have demonstrated the FAEs efficacy in this role (6, 8)