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However, at this time, we cannot discriminate whether the epigenetic modifications are the cause or the consequence of the disease

The reduction of glutathione peroxidase 4 (GPX4), an enzyme that lowers lipid hydroperoxides and inhibits lipid peroxidation, is one important mechanism (67)

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Rodino-Klapac LR, Haidet AM, Kota J, Handy C, Kaspar BK, Mendell JR