[15] [16] For weight management, FDA-approved agents include semaglutide 2.4 mg (Wegovy), tirzepatide (Zepbound), and liraglutide 3 mg (Saxenda), with weight reduction varying by medication (typically 5-15% with liraglutide, 15-20% with semaglutide, and up to 20-25% with tirzepatide)
300,301 This not only affects the intracellular signaling of macrophages but also their response to the external environment, including their effects on chondrocytes and other synovial cells
Avantika Waring, MD, is the Chief Medical Officer at 9amHealth, bringing over fifteen years of clinical and leadership experience
It's designed to complement a healthy lifestyle and support your body's natural GLP-1 response
Studies and real-world experience show that weight regain is common after treatment ends
GLP-1RAs should be discontinued immediately if pancreatitis is suspected and are generally avoided in patients with a prior history of pancreatitis