The pronounced dependence of persistent, drug-resistant malignancies on GPX4 underscores its importance, and its inactivation has the potential to eliminate these cancer cells in vitro and avert tumor recurrence in vivo [216]
For an athlete, a bodybuilder, or someone trying to rapidly repair a severely injured tissue, this raw dump of hormonal support can create incredibly fast tissue repair and anabolism
It's temporary and treatable
Despite convincing data suggesting the central role of GLP-1R signalling in the food intake reduction effects of OXM, there were still some unexplained effects of the gut hormone including increased energy expenditure, suggesting a GLP-1R independent mechanism of action (35)
[1] [2] Other serious risks include pancreatitis, gallbladder disease, acute kidney injury, and diabetic retinopathy complications
The flow diagram of the participants is presented in [Figure 1]