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Together, preclinical models and clinical trials highlight emerging themes of sulforaphane-mediated neuroprotection, including hormetic responses that depend upon the cell/tissue, neurological condition, insult, and developmental stage

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Consequently, the inhibition of EMT emerges as a promising therapeutic strategy

[Abstract]2025 Nov 15:307:119433

GI symptoms, including excessive salivation, dysphagia, constipation, esophageal motility disorders, and gastric abnormalities, occur many years before the appearance of motor symptoms and may be associated with an increased risk of developing PD [112]