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While it found no significant reduction in MACE, it was one of the initial trials that helped expand the safety and tolerability information regarding oral GLP-1 RAs [20]

For most healthy adults, a monitored, lowdose trial of carnitine is reasonable

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A second set of analyses examined people who already had a substance use disorder to see whether they later had substance-related emergency department visits, hospital admissions, deaths, overdoses, or suicidal ideation or attempts

doi: 10.1016/S0140-6736(02)09459-X 66 LeeIHuttemannM