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He delves into the evolutionary and biological role of sleep, emphasizing how it impacts all aspects of our waking lives from immune function and cardiovascular health to mental well-being
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Take all doses in the similar fashion
The jump from 0.5mg to 1mg can trigger temporary side effect resurgence
From an immunological perspective, these associations arise from a breakdown in self-tolerance mediated by overlapping T-cell and B-cell autoreactivity, shared cytokine pathways (e.g., IFN-, IL-18), and common antigen-presenting HLA alleles
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