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PT-141 was safe and well tolerated in both studies

clinical practice uses 2mg injected three times per week (Monday, Wednesday, Friday), totaling approximately 6mg weekly

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Avery Brown, lead study author and surgical resident at NYU Langone Health

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Besides their positive effect on glucose control (mainly by reducing postprandial hyperglycemia), DPP-4 inhibitors showed neutral to modest beneficial effects on body weight, blood pressure (without an increase in heart rate), postprandial lipemia, inflammatory markers, oxidative stress, and endothelial function in patients with T2DM