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& Chen, Z

At sufficiently high concentrations, IGF-1 and its analogs can also engage the insulin receptor directly, which underlies the recognized hypoglycemic (insulin-like) effects of IGF-1 exposure

Once the biological processes activate, they sustain themselves

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The domains III-IV composes an internal ribosomal entry site (IRES) involved in ribosome binding which can initiate viral polyprotein translation in a cap-independent manner[20]

Hadadi, A., Mortezazadeh, M., Kolahdouzan, K