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At the same time, inhibiting NNMT also helps preserve another important molecule: S-Adenosyl Methionine (SAM)

B12 injections help restore your vitamin levels to prevent water loss on your skin and enhance your protection against irritants

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Neurological recovery, if present, can take longer and may not fully reverse if deficiency was severe and longstanding

For this reason, patients with Parkinsons disease on levodopa therapy should avoid high B intake unless they are also taking carbidopa (which prevents this interaction)