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doi: 10.1016/j.fbio.2021.101407 26 BizabaniC.FontenlaS.DamesJ

The oral bioavailability of curcuminoids in healthy humans is markedly enhanced by micellar solubilisation but not further improved by simultaneous ingestion of sesamin, ferulic acid, naringenin and xanthohumol

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Always take supplements with a small amount of food, begin at a lower dose than you think you need, and introduce one new thing at a time so you can tell what is and isnt agreeing with you