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PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation
This matters because a compound that weakly hits three targets would be less useful than one that strongly hits two
Misuse and Misunderstanding: Addressing the Gaps in GLP-1 Therapy While the use of GLP-1 agonists has grown, so has the potential for misuse