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In a mouse model of stroke, intracerebroventricular sodium selenate treatment elevates GPX4 levels by activating transcription factors activating enhancer binding protein 2 and specificity protein 1, while also providing protection against excitotoxicity and endoplasmic reticulum stress-induced cell death independent of GPX4 (102)

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Prevention of type 2 diabetes by lifestyle changes: a systematic review and meta-analysis

However, they serve different functions and operate differently within the body

2, 3, 4 However, despite numerous structural and functional neuroimaging studies, as well as post-mortem investigations, the underlying neurobiological basis of autism continues to remain elusive

Langley SC, Kelly FJ