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10.1080/13543776.2020.1720649 181 ParkJ

According to the study, UA had a direct proinflammatory effect on human macrophages manifested by increased macrophage phagocytic activity, the production of TNF-alpha and toll-like receptor 4 (TLR4), and downregulated the urate anion transporter 1 expression. [ Uric acid is believed to contribute to the antioxidant potential in plasma but within the cell it is rather pro-oxidant

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We conclude that SBM-based diets did not provide adequate glycine for the syntheses of creatine and GSH in growing Phase-I or Phase-II HSB and that dietary supplementation with 1% or 2% glycine is necessary for the maximal growth and feed efficiency, as well as the optimal health (including intestinal health) of these aquatic animals

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